Ceramides are really the best resource plants can directly provide us for our skin health.



With the success of Ceramosides™, Biochemistry PhD and skin science expert, Dr. Valerie Bizot, has firmly planted her feet as the pioneer of plant ceramide chemistry for skin health. Her passion for science and her ability to dive deep into both plant chemistry and skin biology have been the recipe for this winning ingredient. We met with Dr. Bizot to learn more about this story of research and discovery and to get a glimpse into how she developed Ceramosides™.


You’ve been studying plant-based chemistries and human biology for a long time. What would you say was the beginning of your journey to developing Ceramosides™?

Dr. Valerie Bizot: I had focused on both skin health and plant biology for many years, but I really started narrowing down the scope of what I wanted to do and going deeper in 1992. That’s when I began my thesis, “Mechanism of action of plant ceramides to improve skin aging”. At the time, ceramides were known but not studied in depth. So, while I was using my background as the foundation for this work, this is where the process of developing this product really took off. By focusing on one specific target, I was able to explore all the possibilities and continue pushing forward in the right direction.


There are other ingredients that are more commercially well-known, like collagen or hyaluronic acid. Why did you choose to focus on ceramides for skin aging?

Dr. Bizot: Ceramides can have a real impact on the appearance of the skin as they are key components of the dermis and epidermis, providing the first level of protection to the skin and increasing hydration. I was really interested in making a link between plants and the skin - some of the other ingredients are coming from animals, and that wasn’t the direction I wanted to go in. If you look closely at the different elements of the skin and compare them with plants, ceramides are important components of both. They are really the best resource plants can directly provide us for our skin health.


What would you say makes Ceramosides™ really unique in its category?

Dr. Bizot: Ceramosides™ is composed of two main lipids, phytoceramides and DGDG. This specific combination can only be obtained from wheat. The goal of the patented process that we have developed was to get the optimum ratio of these lipids to get the most efficient product out there - and gluten free. Our clinical studies have confirmed the superior efficiency on improving skin moisture and wrinkles with improvements measured after only 15 days. In perfecting the process, we’ve been able to concentrate the lipids, allowing a very small clinical dose. The low dose opens a wide range of innovative formulating options in both nutrition (e.g. powder drinks, gummies, chews) and cosmetics. In fact, the benefits of Ceramosides™ have been studied for both applications - nutritional and cosmetic - Ceramosides™ products can be used at the same time to achieve beautiful skin from the inside and out!

I think this is going to quickly become one of the most exciting and innovative ingredients in the healthy aging category.


Podcast: Danielle Lin, The art of living and science of life - Episode name: CERAMOSIDES™: Ingredients for Health and Beauty  


Danielle Lin:  “From your perspective as a pharmacist, looking at a breakthrough nutritional like Ceramosides™, what was so interesting about it for you?”

Sherry Torkos: “What really intrigued me was that it has the ability to improve our skin all over our body not just our face but our neck, and our arms, our chest, our whole body in fact, because it really works on the cellular level, to help increase hydration to address some of the concerns that people have with aging, premature wrinkling, dryness, that pulling sensation in their face. So I thought that was very interesting, this is something you take orally that can have a really profound effect on the health and the aging of the skin, very safe, very well tolerated. And here’s what’s also very interesting, is it works fairly quickly, for an oral product people will notice a benefits within about 2 weeks once they start supplementing with it.”

DL: “It comes in different forms, correct? Is this in tablets, or which way is it delivered”

ST: “That’s right, you may actually see it in capsules, there is both a powder and liquid, and this is something that can be put into capsules, tablets, powder sticks, beverages, nutrition bars. It offers really those whole body skin benefits. You know I think that was one of the things that I really tweaked my curiosity is the research behind it, the fact that it has this whole body effect and the company has really done their homework. This ingredient has actually been sold in Europe for 10 years, it’s now in North America and I think this is going to quickly become one of the most exciting and innovative ingredients in the healthy aging category.”

DL: “Yea, I have to agree with you, I had a big famous salon in Hollywood for many many years in the film industry and we did a lot of breakthrough stuff but this i think is in the leading edge of where we are heading in the beauty industry and it couldn't be more important, at a perfect time.”

DL: [Ceramosides™] It’s complimentary with others things that I had asked about with like collagen and hyaluronic acid, can you talk a little bit about that, along with the mechanism of action.

ST: There hasn’t been anything on the market that I have seen that has this level of evidence for helping to really target these ceramides, which we know are so critical for the health and appearance of the skin. [...] At the skin level the Ceramosides™ help to again, enhance the ceramides, which are part of the skin barrier, part of the integral lipid area of the skin, so helping to restore water balance to keep skin hydrated, replenish those cracks, and there’s also in-vitro data to show that it helps to prevent collagen degradation by inhibiting an enzyme [collagenase], so we do know that it has those mechanisms and it is not just an ingredient again that is going to benefit the face, you take it orally and you get the full body effect.


Guest: Sherry Torkos, R. Ph., Holistic pharmacist, author and Certified Fitness Instructor


Sherry Torkos is a pharmacist, author, certified fitness instructor and health enthusiast who enjoys sharing her passion with others. Sherry graduated with honors from the Philadelphia College of Pharmacy and Science in 1992. Since that time she has been practicing holistic pharmacy in the Niagara region of Ontario. Her philosophy of practice is to integrate conventional and complementary therapies to optimize health and prevent disease. Sherry has won several national pharmacy awards for providing excellence in patient care. Sherry has authored 18 books and booklets, including The Canadian Encyclopedia of Natural Medicine, Saving Women’s Hearts, and The Glycemic Index Made Simple.

Gene Bruno
As a scientist, I need proof that the use of a given ceramide material will actually work. That’s why I like Ceramosides™.

While the role of ceramides is well established in helping to form a protective barrier within the skin to help maintain moisture and prevent dry skin, that does not mean that supplementing or topically applying just any ceramide product will result in a beneficial effect on the skin. Ceramide materials are different, as are the way they are absorbed and utilized by the body. As a scientist, I need proof that the use of a given ceramide material will actually work. That’s why I like Ceramosides™. Human research has demonstrated that both supplementation and application of Ceramosides™ as a topical cream resulted in meaningful differences, including improvements in skin moisturization, elasticity, and roughness. The data shows that Ceramosides™ is a science-based, albeit naturally-derived, and effective ingredient.

Gene Bruno
Professor of Nutraceutical Science - Huntington College of Health Sciences

Gene Bruno is Professor of Nutraceutical Sciences and Provost of Huntington College of Health Sciences. Prof. Bruno has two undergraduate Diplomas in Nutrition, a Bachelor’s in Nutrition, a Master’s in Nutrition, a Graduate Diploma in Herbal Medicine, and a Master’s in Herbal Medicine. He also headed the team that developed a Doctorate program in Integrative Healthcare at Huntington, as well as writing several of the courses for that program. For over 35 years Prof. Bruno has educated and trained healthcare professionals as well as natural product retailers in nutrition and nutraceutical sciences. He has also researched and
formulated hundreds of natural products for dozens of dietary supplement companies, and has written articles on nutrition, herbal medicine, nutraceuticals and integrative health issues for trade, consumer magazines, and peer-reviewed publications. Most recently, Prof. Bruno authored two textbook chapters: “Sexual Dysfunctions and Nutraceutical Therapy: An examination of Human Research”, for Nutaceuticals and Functional Foods in Human Health and Disease Prevention (2015, CRC Press), and “Pomegranate Juice and Extract”, for Fruits, Vegetables and Herbs (2016, Academic Press).

Maday Labrador
Plant-derived phytoceramides […] can be ingested daily to naturally protect against moisture loss and support the skin’s structure.

In my new book, Happy Cells Healthy You, I discuss the significance of supplementation and receiving nutrients from the foods we eat, and how what we feed our cells affects our health and beauty. When we are well nourished, the body functions and looks its best!

The skin is the body’s largest organ and requires both nourishment and elimination. Accordingly, skin problems are often a reflection of poor nutrition. Too much refined foods and sugars, saturated fats, and caffeine may cause redness, blotching and accelerated skin aging.  

While we may not be able to stop the physical signs of skin aging, there is a growing body of scientific research that suggests that a nutritious diet promotes skin health and delays skin aging. Many plant-based foods provide vitamins, minerals, and fatty acids that are needed for healthy and youthful-looking skin. As well, let’s not forget the importance of good water intake.

Hydration is extremely important for skin health. Water plumps up skin cells, reducing wrinkles and dryness. Water also helps to flush out toxins.  Hydrating is different than moisturizing. Hydrating adds moisture into the skin, while moisturizing seals in moisture. Your skin needs both.

A balanced diet of fruits, vegetables, and lots of good water is a quick and healthy way to support healthy skin. As we age, though, even with a healthy diet, supplementation is often needed. Our skin undergoes several changes, including the breakdown of collagen and elastin and difficulties hydrating and retaining moisture. With age, ceramides production declines. They are part of the skin’s natural protective barrier that helps retain moisture levels. When the supply of ceramides in the body slows down, the skin tends to form wrinkles and lose its supple appearance.  

However, plant-derived phytoceramides mimic the attributes of ceramides and can be ingested daily to naturally protect against moisture loss and support the skin’s structure, function, and appearance. After absorption into the bloodstream, they are transported through the skin levels, where they have been proven to help restore the water barrier. This is why I recommend Ceramosides™ in my book.

Maday Labrador, Ph.D in Holistic Nutrition
President of Global Health Naturals Nutritional Supplements


Maday Labrador holds a Ph.D in Holistic Nutrition and has been working in the natural health industry for the last 18 years, accumulating expertise on nutritional wellness and lifestyle. Maday has spoken to thousands of retailers and consumers on the importance of a whole-body approach to health and wellness. Currently President of Global Health Naturals Nutritional Supplements, she previously served as Vice President of Education and Scientific Affairs for Enzymedica and also wrote articles, conducted lectures, radio interviews and consultations on behalf of the company.